KIM, HONG WOO,KOH, JONG SUNG,LEE, JAEKYOO,SONG, HO-JUHN,KIM, YOUNGSAM,LEE, HEE KYU,CHOI, JANG-SIK,LIM, SUN-HEE,CHANG, SUNHWA
申请号：
SG2012027488
公开号：
SG180375A1
申请日:
2010.10.29
申请国别(地区):
SG
年份:
2012
代理人:
摘要：
The present invention provides a new group of protein kinase inhibitors, pyrido[4,3,-d]pyrimidin-5-one derivatives, and pharmaceutically acceptable salts thereof that are useful for intreating cell proliferative disease and disorder such as cancer, autoimmune diseases, infection, cardiovascular disease and neurodegenerative disease and disorder. The present invention provides methods for synthesizing and administering the protein kinase inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the protein kinase inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefor. The invention also provides useful intermediates generated during the syntheses of the pyrido[4,3,-d]pyrimidin-5-one derivatives.
