The present invention provides, in part, compositions comprising an inhibitor of cyclin-dependent kinase 7 (CDK7) and sulfobutyl ether-β-cyclodextrin. Also provided are methods of using a disclosed composition for treating proliferative diseases. The present invention also provides methods of making disclosed compositions.本發明部分地提供包含週期素依賴型激酶7 (CDK7)之抑制劑及磺酸基丁基醚-β-環糊精之組合物。亦提供使用所揭示之組合物用於治療增生性疾病之方法。本發明亦提供製備所揭示之組合物之方法。