Meredith M. Lee,Jelena Levi,James L. Zehnder,James S. Harris, JR.
申请号:
US14752144
公开号:
US20150374269A1
申请日:
2015.06.26
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Improved monitoring of one or more blood coagulation factors is provided. Factor-specific molecular probes having a dye-quencher arrangement are employed. In preferred embodiments, a compact integrated optical source and detector device is used for fluorescence measurements. Continuous and real-time monitoring of the activity of one or multiple blood factors is provided. Such real-time information can be used to automatically control delivery of drugs such as coagulants and/or blood thinners.