PURPOSE: A lymphoduct generation inducer containing erythropoietin is provided to induce lymphduct through Akt/ERK pathway in human lymph vascular epithelial cells. CONSTITUTION: A lymphoduct generation inducer contains erythropoietin as an active ingredient. A composition for preventing or treating lymphedema contains erythropoietin as an active ingredient. A composition for preventing or treating lymphoduct loss or lymphopenia contains the erythropoietin as an active ingredient.본 발명은 에리스로포이에틴을 유효 성분으로 포함하는 림프관 생성 유도제에 관한 것이다. 에리스로포이에틴은 사람 림프혈관내피세포에서 Akt/ERK 경로를 통하여 림프관 생성을 유도할 수 있다.