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Pyridin-2-amides useful as CB2 agonists
- 专利权人:
- F. Hoffmann-La Roche AG
- 发明人:
- BISSANTZ, Caterina,GRETHER, Uwe,HEBEISEN, Paul,KIMBARA, Atsushi,LIU, Qingping,NETTEKOVEN, Matthias,PRUNOTTO, Marco,ROEVER, Stephan,ROGERS-EVANS, Mark,SCHULZ-GASCH, Tanja,ULLMER, Christoph,WANG, Zhiwei
- 申请号：
- ES12725834
- 公开号：
- ES2588327T3
- 申请日:
- 2012.06.07
- 申请国别(地区):
- ES
- 年份:
- 2016
- 代理人:
- 摘要：
- A compound selected from methyl 2-methyl-2- (5-methyl-6- (2,2,2-trifluoroethoxy) picolinamide) propanoate； 2 - [(6-Cyclohexyl-pyridin-2-carbonyl) -amino] -2-methyl-propionic acid methyl ester； 2 - {[6-Cyclopropylmethoxy-5- (tetrahydro-pyran-4-yl) -pyridin-2-carbonyl] -amino} -2-methyl-propionic acid methyl ester； 6-Cyclopropylmethoxy-5- (tetrahydro-pyran-4-yl) -pyridine- [1-methyl-1- (5-methyl- [1,2,4] oxadiazol-3-yl) -ethyl] -amide 2- carboxylic； 2 - {[6-Cyclopropylmethoxy-5- (1 H -pyrazol-3-yl) -pyridin-2-carbonyl] -amino} -2-methyl-propionic acid methyl ester； 6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridin-2-carboxylic acid ((S) -1-hydroxymethyl-3-methyl-butyl) -amide； (6-cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridin-2-yl) - (1,1-dioxidotetrahydro-2H-thiopiran-4-yl) -methanone； (6-cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridin-2-yl) -thiomorpholin-4-yl-methanone； 6-Cyclohexyl-pyridin-2-carboxylic acid piperidin-1-ylamide； [5-methyl-6- (piperidin-1-sulfonyl) -pyridin-2-yl] -piperidin-1-yl-methanone； 2 - [(6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridin-2-carbonyl) -amino] -2-methyl-propionic acid methyl ester； (6-cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridin-2-yl) - (2-oxa-6-aza-spiro [3.3] hept-6-yl) -methanone； 6-Cyclopropylmethoxy-5- (2-methyl-pyrrolidin-1-yl) -pyridine-2-carboxylic acid ((S) -1-carbamoyl-3-methyl-butyl) -amide； 6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carboxylic acid [1-methyl-1- (5-methyl- [1,2,4] oxadiazol-3-yl) -ethyl] -amide； 6-Cyclopropylmethoxy-5- (tetrahydro-pyran-4-yl) -pyridine-2-carboxylic acid (1-methyl-1-thiazol-2-yl-ethyl) -amide； 6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridin-2-carboxylic acid (1,1-dimethyl-3-morpholin-4-yl-propyl) -amide； 6-Cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acid (1-methyl-1-methylcarbamoyl-ethyl) -amide； 6- (tetrahydro-pyran-4-yl) -pyridin-2-carboxylic acid piperidin-1-ylamide； (5-cyclopentyl-6-cyclopropylmethoxy-pyridin-2-yl) - (1,1-dioxidotetrahydro-2H-thiopiran-4-yl) -methanone； 5-Cyclopen
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
