GENE FOR PERIPHERAL ARTERIAL OCCLUSIVE DISEASE

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专利权人:

DECODE GENETICS EHF.;GUDMUNDSSON, GUDMUNDUR

发明人:

GUDMUNDSSON, GUDMUNDUR

申请号：

WO2003IB00300

公开号：

WO03064471(A3)

申请日:

2003.01.29

申请国别(地区):

世界知识产权组织国际局

年份:

2003

代理人:

摘要：

A role of the human PAOD1 gene, a. k. a. prostaglandin E receptor subtype EP3 or PTGER3, in peripheral arterial occlusive disease is disclosed, as are nucleic acids encoding several subtypes of the receptor comprising novel exons 4 and 5. Methods for diagnosis, prediction of clinical course and treatment for peripheral occlusive disease using polymorphisms in the PAOD1 gene are also disclosed.

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