NATIONAL UNIVERSITY OF SINGAPORE;UNIVERSITY OF MYSORE;BANGALORE UNIVERSITY
发明人:
Peter Edward Lobie,Vijay Kumar Pandey,Ranpappa Kanchugarakoppal Subbegowda,Bassappa Salundi,Mohan Chakrabhavi Dhananjaya,Shobith Rangappa,Srinivasa Venkatachalaiah
申请号：
US16605630
公开号：
US20200131139A1
申请日:
2018.04.18
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention relates to compounds of general formula (I): wherein R1, n, R2a, R2b, and R3 are as defined herein. The compounds are inhibitors of Bcl-2-associated death promoter (BAD) phosphorylation and have anti-apoptotic activity and are useful in the treatment of cancer, particularly breast cancer, endometrial cancer, ovarian cancer, liver cancer, colon cancer, prostate cancer or pancreatic cancer.
