Roland K. Strong,Mesfin Gewe,Martin Prlic,Peter Rupert,Thomas Spies,Veronika Spies
申请号：
US15775298
公开号：
US20180371051A1
申请日:
2016.11.10
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Single chain, multimerized, and/or glycosylated NKG2D decoys are described. The NKG2D decoys have high affinity and avidity for surface bound and soluble NKG2D ligands and can be used to (i) identify NKG2D ligands (ii) treat cancer, graft vs. host disease (GVHD), and inflammatory conditions and (iii) potentiate an immune response against a vaccine as well as many other potential uses.
