WEINSCHENK TONI,MAHR ANDREA,FRITSCHE JENS,MLLER PHILLIP,WIEBE ANITA,KUTSCHER SARAH
申请号：
IN201747021688
公开号：
IN201747021688A
申请日:
2017.06.21
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The present invention relates to peptides proteins nucleic acids and cells for use in immunotherapeutic methods. In particular the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor associated T cell peptide epitopes alone or in combination with other tumor associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti tumor immune responses or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC) or peptides as such can also be targets of antibodies soluble T cell receptors and other binding molecules. In particular the present invention relates to several novel peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti tumor immune responses or as targets for the development of pharmaceutically / immunologically active compounds and cells.
