Nikolai Eroshenko,Nikhil Dhar,Taylor Gill,Marianna Keaveney,Hannu Rajaniemi
申请号:
US16649105
公开号:
US20200224194A1
申请日:
2018.09.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Nucleic acid expression systems are provided herein that include a first synthetic oligonucleotide comprising a payload sequence and a second synthetic oligonucleotide comprising a sequence that encodes a helper polypeptide. Compositions (e.g., pharmaceutical compositions) comprising the nucleic acid expression systems as well as methods of using the same are also provided herein.