Compositions and methods are provided for a combination of a new strain of Bacillus amyloliquefaciens RTI301 and a new strain of Bacillus subtilis RTI477, the combination having growth promoting activity and activity against plant pathogens. The compositions containing the RTI301 and RTI477 strains are useful for benefiting plant growth and/or conferring protection against a pathogenic infection when applied to plant roots, seeds, callus tissue, grafts, and cuttings. Synergistic results are observed for the combination of the strains, and the combination of strains is useful to increase yield in crops including soybean and corn. The compositions containing the combination of strains can be applied alone or in combination with other microbial, biological, or chemical insecticides, fungicides, nematicides, bacteriocides, herbicides, plant extracts, plant growth regulators, and fertilizers.本發明提供關於解澱粉芽孢桿菌RTI301新菌株與枯草芽孢桿菌RTI477新菌株之組合的組合物及方法,該組合具有促生長活性及對抗植物病原體之活性。當含有RTI301及RTI477菌株之該等組合物施用於植物根部、種子、癒合組織、移植物及插條時,有用於有益於植物生長及/或賦予保護以避免病原性感染。觀測到此等菌株之組合的協同結果,且菌株組合適用於增加包括大豆及玉米之作物的產量。含有該等菌株組合之該等組合物可單獨或與其他微生物、生物或化學殺蟲劑、殺真菌劑、殺線蟲劑、殺菌劑、除草劑、植物提取物、植物生長調節劑及肥料組合施用。