Joost J. Neijssen,Joyce I. Meesters,Bart De Goeij,Aran Frank Labrijn,Paul Parren,Janine Schuurman
申请号:
US14112859
公开号:
US20140170149A1
申请日:
2012.04.20
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Bispecific antibodies which comprise one antigen-binding region binding to an epitope of human epidermal growth factor receptor 2 (HER2) and one antigen-binding region binding to human CD3, and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and methods for preparing and using the antibodies are also disclosed.