The present invention relates to compositions comprising an alpha- adrenoceptor ligand for use in the treatment of benign anorectal conditions, in particular haemorrhoids. In addition to an alpha-adrenoceptor ligand, the compositions of the inventions may additionally include a calcium channel activator. Compositions with guanfacine and S(-)BayK8644 are preferred.Linvention concerne des compositions comprenant un ligand α-adrénocepteur destiné à être utilisé dans le traitement daffections ano-rectales bénignes.