Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via isocyanate using azides and carbon-isotope monoxide

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专利权人:

Bengt Langstrom

发明人:

Bengt Langstrom,Julien Barletta,Hisashi Doi,Masaaki Suzuki,Ryoji Noyori,Yasuyoshi Watanabe,Farhad Karimi

申请号：

US11086632

公开号：

US08741261B2

申请日:

2005.03.22

申请国别(地区):

US

年份:

2014

代理人:

摘要：

Methods and reagents for transition metal-promoted carbonylation via isocyanate using carbon-isotope labeled carbon monoxide are provided. The resultant carbon-isotope labeled compounds are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.

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