FEDERALNOE GOSUDARSTVENNOE BJUDZHETNOE NAUCHNOE UCHREZHDENIE "NAUCHNYJ TSENTR PROBLEM ZDOROVJA SEMI I REPRODUKTSII CHELOVEKA"
发明人:
BOLSHAKOVA SVETLANA EVGENEVNA,Большакова Светлана Евгеньевна,DOLGIKH VLADIMIR VALENTINOVICH,Долгих Владимир Валентинович,BUGUN OLGA VITALEVNA,Бугун Ольга Витальевна,ZURBANOV ANDREJ VJACHESLAVOVICH,Зур
申请号：
RU2014124398/14
公开号：
RU0002550722C1
申请日:
2014.06.16
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
FIELD: medicine.SUBSTANCE: method includes determining factors of a risk of essential arterial hypertension (EAH) development in young men with haemocoagulation disorders. For this purpose determined are: X1 - level of fibrinogen in blood, g/l X2 - level of soluble fibrin-monomer complexes in blood, mg/dl X3 - level of high-density lipoproteins in blood, mmol/l X4 - a complicated course of pregnancy. 1 is given if the pregnancy was without complications, 0 - if the pregnancy was with complications. X5 - late gestosis. 1 is given if no gestosis was registered during the pregnancy, 0 - if gestosis was registered during the pregnancy X6 - index of AH in a family, with 1 - if in the family there are relatives, suffering from AH, 0 - if in the family there are no relatives, suffering from AH X7 - index of thrombosis in the family in relatives, with 1 - if in the family there are relatives, who had thrombosis, 0 - if in the family there are no relatives after thrombosis X8 - excessive weight, with 1 - yes, 0 - no X9 - type of the left ventricular ejection. 1 is the normal kinetic type, 2 is the hyperkinetic type, 3 is the hypokinetic type X10 - type of the left ventricle filling, 1 is normal functional, 2 is hyperfunctional, 3 is rigid. After that prognostic coefficients F1 and F2 are calculated by formulae F1=-0.65-0.53×X1+0.21×X2+0.81×X3+0.45×X4+0.52×X5-0.63×X6-0.87×X7+0.36×X8-0.21×X9-0.88×X10, F2=-2.74+1.27×X1-0.69×X2-0.54×X3-0.83×X4-0.38×X5-0.44×X6+0.92×X7-0.58×X8+0.95×X9+0.62×X10. If F1>F2, the prediction is favourable, the probability of EAH development is considered to be low. If F2>F1, the prediction is unfavourable, the probability of EAH development is high.EFFECT: method increases the accuracy of predicting the risk of EAH development in young men with haemocoagulation disorders, which makes it possible to start taking preventive measures aimed at the reduction of frequency of thrombosis development in due time.2 exИзобретение относится к медицине, а именно к п
