Jing Zeng,Charles George Drake,Drew M. Pardoll,Michael Lim
申请号：
US14127597
公开号：
US09132281B2
申请日:
2012.06.19
申请国别(地区):
US
年份:
2015
代理人:
摘要：
An approach combining immune-based therapies with focused radiation, including stereotactic radiation, to treat cancers is disclosed. The use of focused radiation primes the immune system in a similar manner to vaccines to augment immune-based therapies and can counteract the suppressive effects of a tumor. The combination of focused radiation and immune-based therapies, including administration of at least one immunotherapeutic agent, improves survival compared to each therapy alone and can, in some cases, lead to a durable cure. Accordingly, focused radiation can be an adjuvant for immune-based therapies for treating cancers.
