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Substituted aminopropionic acid derivatives as neprilysin inhibitors
专利权人:
NOVARTIS AG
发明人:
SUN, ROBERT,COPPOLA, GARY MARK,IWAKI, YUKI,KARKI, RAJESHRI GANESH,KAWANAMI, TOSHIO,KSANDER, GARY MICHAEL,MOGI, MUNETO
申请号:
DK10720165
公开号:
DK2435409T3
申请日:
2010.05.26
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
The present invention provides a compound of formula I'; or a pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 , R 5 , B 1 , X and n are defined herein. The invention also relates a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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