PROBLEM TO BE SOLVED: To provide a sirtuin activator that is inexpensive and made from natural products, which is more easily available and stronger than resveratrol.SOLUTION: A sirtuin activator contains black turmeric, or black turmeric extract, and a polyalkoxy flavonoid compound of formula (I) as an active ingredient (R1-R7 are a lower alkoxy group, a hydrogen atom or a hydroxy group).SELECTED DRAWING: None【課題】レスベラトロールより入手しやすく、かつより強い、安価な天然物系のサーチュイン活性化剤の提供。【解決手段】黒ウコン、または黒ウコン抽出物、また式(I)のポリアルコキシフラボノイド類化合物を有効成分とするサーチュイン活性化剤。(R1~R7は低級アルコキシ基、水素原子または水酸基を表す)。【選択図】なし