Dennis S. Charney,Sanjay J. Mathew,Husseini K. Manji,Carlos A. Zarate, Jr.,John H. Krystal
申请号：
US11688603
公开号：
US08785500B2
申请日:
2007.03.20
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal administration of ketamine is effective to ameliorate the symptoms of depression in a patient who has not responded to an adequate trial of one antidepressant in the current episode and has recurrent or chronic depressive symptoms (>2 years).
