COMPOSITIONS COMPRISING ALBUMIN-FMS-LIKE TYROSINE KINASE 3 LIGAND FUSION PROTEINS AND USES THEREOF

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专利权人:

THE JOHNS HOPKINS UNIVERSITY

发明人:

T.C. Wu,Chien-Fu Hung,Brandon Krishna Lam

申请号：

US16244200

公开号：

US20190209649A1

申请日:

2019.01.10

申请国别(地区):

US

年份:

2019

代理人:

摘要：

The present invention provides a novel fusion protein of Flt3L and albumin and its use to increase the Flt3L half-life in vivo and to deliver Flt3L to immune cells in a subject to enhance alternative dendritic cell populations. Use of the fusion protein in combination with other chemotherapeutic, radiotherapeutic and immunotherapeutic methods are also provided.

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