A device for skin treatment by concurrently applying a series of physical movement such as ultrasound vibration and dispensing a specimen to a target kin area is disclosed. The device includes a skin treatment surface for treating the target skin area, a cartridge containing specimen to be dispensed to the target skin area, an ultrasound generator, a control unit and a power supply. A specimen outlet is on the kin treatment plate. The outlet is coupled to the cartridge.