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Dry powder formulations of particles that contain two or more active ingredients for treating obstructive or inflammatory airways diseases
专利权人:
Danforth Miller;Thomas E. Tarara;Nagaraja Rao;Daniel Huang;Jeffry G. Weers
发明人:
Jeffry G. Weers,Nagaraja Rao,Daniel Huang,Danforth Miller,Thomas E. Tarara
申请号:
US13982630
公开号:
US20130319411A1
申请日:
2012.02.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Dry powder formulations for inhalation comprising spray-dried particles and their use in the treatment of an obstructive or inflammatory airways disease. Each particle has a core of a first active ingredient in substantially crystalline form that is coated with a layer of a second active ingredient in substantially amorphous form that is dispersed in a pharmaceutically acceptable hydrophobic excipient. A process for preparing such formulations is also described.
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