A medical imaging system including a microwave antenna array having a transmitting antenna and a plurality of receiving antennae, wherein the transmitting antenna is configured to transmit microwave signals so as to illuminate a body part of a patient and the receiving antennae are configured to receive the microwave signals following scattering within the body part; a processor configured to process the scattered microwave signals and generate an output indicative of the internal structure of the body part to identify a region of interest within the body part; and a biopsy device comprising a biopsy needle movable relative to the microwave antenna array; wherein the receiving antennae are further configured to receive microwave signals scattered or emitted by the biopsy needle and the processor is further configured to monitor a position of the biopsy needle and to guide the biopsy needle to the identified region of interest within the body part.