Compositions for CYP450 phenotyping using saliva samples

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专利权人:

Concordia University Inc.

发明人:

McGraw, Joseph,Gerhardt, Armin Henry

申请号：

AU2016365229

公开号：

AU2016365229A1

申请日:

2016.11.30

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

Disclosed are methods and compositions which may be used in human cytochrome P450 (CYP450) enzyme phenotyping. The methods and compositions typically utilize a melange of substrates for different CYP450 enzymes which may be administered orally to a patient. Subsequently, the metabolites of the substrates may be detected in the patient's saliva as well as any non-metabolized substrates to calculate a metabolic ratio for any given CYP450 enzyme in order to generate a phenytopic CYP450 enzyme profile for the patient.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/