The United States of America; as represented by the Secretary Department of Health and Human Service
发明人:
Martin John Schnermann,Roger Rauhauser Nani,Alexander Patrick Gorka,Hisataka Kobayashi
申请号：
US16723482
公开号：
US20200121790A1
申请日:
2019.12.20
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Embodiments of near-infrared light-cleavable heptamethine cyanine-based conjugates, particularly targeting agent-drug conjugates, according to Formula I and conjugate precursors are disclosed. The disclosed targeting agent-drug conjugates are useful for targeted delivery and release of a drug. Methods of making and using the conjugates and precursors also are disclosed.
