Karl Gunnar Bjursell,Jeanette Annika Nilsson,Sara Ellmark
申请号：
US13291731
公开号：
US20120053114A1
申请日:
2011.11.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention provides methods of screening test compounds for their ability to reduce retention of atherogenic lipoproteins in atherogenesis by measuring their activity as a modulator of the binding affinity of CEL (Carboxyl Ester Lipase) to various receptors. The invention further provides methods for the use of active modulators of the binding affinity of CEL to receptors for the prevention and treatment of atherosclerosis.
