The present invention provides a pharmaceutical composition administered in combination with other medicaments. The pharmaceutical composition contains a specific substituted biaryl compound or a pharmacologically acceptable salt thereof. The pharmaceutical composition of the present invention is useful as a treating drug and/or a preventing drug for respirator disease such as asthma, chronic obstructive pulmonary disease, bronchitis, emphysema, pulmonary fibrosis, acute respiratory distress syndrome, Cystic Fibrosis and pulmonary hypertension.本發明提供一種與其他的醫藥組合而投予的醫藥組成物，且該醫藥組成物係含有特定的取代聯芳基化合物或其藥理上可容許的鹽。本發明的醫藥組成物是，作為對於氣喘、慢性阻塞性肺疾病、支氣管炎、肺氣腫、肺纖維症、急性呼吸窘迫症候群、囊腫性纖維症及肺性高血壓症等呼吸器官疾病的治療藥及/或預防藥而有用。
