Fisher, Kerry,Bhatia, Jeetendra,Champion, Brian Robert
申请号:
AU2014222610
公开号:
AU2014222610A1
申请日:
2014.02.28
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The present disclosure relates to a process for the manufacture of adenoviruses wherein the process comprises culturing mammalian cells infected with the adenovirus in the presence of media suitable for supporting the cells such that the virus replicates, wherein the cells are capable of supporting viral replication, and at the end of the culturing period isolating from the media the adenovirus by filtering wherein the isolation of virus is not subsequent to a cell lysis step and to viruses obtainable from the process.