Phosphate Salt of 5-methyl-4-oxo-1,4-dihydropyrrolo [1,2-c] imidazolilo, aldosterone synthase or aromatase inhibitor； nitrate salt； Crystal form； a procedure for preparing a Crystalline Salt nitrate or phosphate； Pharmaceutical Composition and its use for the treatment of Cushing's Syndrome.

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专利权人:

NOVARTIS AG.

发明人:

SUTTON PAUL,LOESER ERIC

申请号：

CL2014001863

公开号：

CL2014001863A1

申请日:

2014.07.15

申请国别(地区):

CL

年份:

2014

代理人:

摘要：

The invention relates to a phosphate salt or a nitrate salt of 4-(R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl-3-fluoro-benzonitrile, especially in crystalline form, and specific forms of these salts, as well as related invention embodiments. The salts and salt forms allow for the prophylactic and/or therapeutic treatment of aldosterone synthase and/or aromatase mediated diseases or disorders.SAL FOSFATO CRISTALINA DE 4-(R)-(6,7-DIHIDRO-5H-PIRROLO [1,2-C] IMIDAZOL-5-IL)-3-FLUOROBENZONITRILO, PROCESO DE PREPARACIÓN, ÚTIL PARA EL TRATAMIENTO DEL SÍNDROME DE CUSHING.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/