#$%^&*AU2015201076B220170112.pdf#####ABSTRACT This invention provides an effective means or method for improving lipid metabolism, and a means or method for treatment or prevention of diseases or disorders associated with the lipid metabolism disorder. Specifically, this invention relates to an agent for improving the lipid metabolism comprising, as active ingredients, broken cells of a lactic acid bacterium, and to a method for enhancing an effect of a lactic acid bacterium for improving the lipid metabolism comprising a step of breaking the lactic acid bacterium.Fig. 1 A B 1/9Fig. 2 Experiment 1 160 140 0 0 120 80 Control Undisrupted cells Disrupted cells 2/9Fig. 3 Experiment 2 120 2* -6 100 Y80 80 Control Uncrupted Disrupted cells CP3238 3/9Fig. 4 140 o7 120 5 0 100 y~ 460 0.00% 0.25% 0.50% 1.00% Percentage of disrupted CP1563 cells incorporated 4/9Fig. 5 140 120 C 0 o* 0 100 80 60 0.00% 0.25% 0.50% 1.00% Percentage of disrupted CP1563 cells incorporated 5/9Fig. 6 A B 140 - 140 2 LT ) 120 -(Pn 120 - 1 100 -100 80 80 60 60 Control Disrupted Control Disrupted CP1563 cells CP1563 cells C D 140 - 140 2 120 - 2120 LIE- D) 100 - 0 100 4-3C4, 4-Z 80 - 80 60 60 Control Disrupted Control Disrupted CP1563 cells CP1563 cells E F C-, + 140 - 140 0 0-" 120 - 120 100 -100 80 o -0 0 80 E 60 >； c60 Control Disrupted Control Disrupted CP1563 cells CP1563 cells 6/9Fig. 7 120 * W5 100 Control Disrupted cells CP1563 Organic solvent extract 7/9Fig. 8 130% 120% 0 110% :0 100% - -90% Control Disruption 1 Disruption 2 Disruption 3 (87%) (68%) (16%) CP1563 8/9Fig. 9 140% * * 130% 120% Uo8 110% 100% 90% Control Disrupted Disrupted CP1563 cells CP1562 cells 9/9
