תכשירים ושיטות לבקרת הפעלה ותפקוד של תאי הרג טבעיים )תאי nk (natural killer)(
- 专利权人:
- BAR ILAN UNIVERSITY
- 发明人:
- 申请号:
- IL26812919
- 公开号:
- IL268129D0
- 申请日:
- 2019.07.17
- 申请国别(地区):
- IL
- 年份:
- 2019
- 代理人:
- 摘要:
- The present invention provides means to affect the dynamics of actomyosin network in natural killer (NK) cells, and thereby to confer selective control on killing efficiencies of NK cell populations. Compositions and methods of the present invention, particularly those using small molecules, provide a powerful tool for controlling NK cell activation and function in various conditions, in health and disease, most notably in viral infections, autoimmunity, immunodeficiency, GVHD and cancer.
- 来源网站:
- 中国工程科技知识中心
相关发明人
相关专利
- B CELL ACTIVATION INHIBITOR, AND THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASES
- Multispecific NK engager protein
- PHARMACEUTICAL COMPOSITION FOR TREATING FATTY LIVER DISEASE AND HEALTH FUNCTIONAL FOOD FOR IMPROVING LIVER FUNCTION CONTAINING EXTRACT OR POWDER OF PLEUROTUS ERYNGII AS ACTIVE COMPONENT
- B Cell Activation Inhibitor, and Therapeutic Agent For Autoimmune Diseases
- COMPOUND FOR STIMULATING SIGNAL PATHWAYS THROUGH IL-15RBETA/GAMMA FOR PURPOSES OF INDUCING AND/OR STIMULATING ACTIVATION AND/OR PROLIFERATION OF IL-15RBETA/GAMMA-POSITIVE CELLS SUCH AS NK- AND/OR T-CELLS, NUCLEIC ACID CODING COMPOUND, EXPRESSION VECTOR, HOST CELL, ADJUVANT FOR IMMUNOTHERAPEUTIC COMPOSITION, PHARMACEUTICAL COMPOSITION AND THERAPEUTIC AGENT FOR TREATING CONDITION OR DISEASE WHICH REQUIRES HIGHER ACTIVITY OF IL-15, METHOD FOR INDUCING AND/OR STIMULATING IN VITRO PROLIFERATION AND/OR ACTIVATION OF IL-15RBETA/GAMMA-POSITIVE CELLS AND METHOD FOR MAKING IN VITRO ACTIVATED NK-AND/OR T