Yili Ding,Xuan Yang,Qingyan Yan,Hua Bai,Lifeng Cai,Kenneth Smith,Jian Chai
申请号:
US14342656
公开号:
US09221798B2
申请日:
2011.09.05
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Provided are derivatives substituted by urea associated with 4-substituted-(3-substituted-1H-pyrazole-5-amino)-pyrimidine-2-amino of formula (I), wherein these compounds may selectively regulate or inhibit an information transmission process controlled by natural or variant tyrosine kinase. Also provided are preparation methods and uses of the compounds.