Rajashree Joshi-Hangal,Nipun Davar,Stephen R. Priebe
申请号：
US16053354
公开号：
US10519190B2
申请日:
2018.08.02
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention provides a method of preparing a lyophilized pharmaceutical composition containing a compound described herein or a pharmaceutically-acceptable salt thereof. The process comprises dissolving the compound in a solvent comprising dimethylsulfoxide and optionally one or more co-solvents to form a solution, and then removing the solvent and any co-solvents by a freeze-drying process. Also provided by the invention are lyophilized pharmaceutical compositions and their use in medicine and in particular in the treatment of cancer.
