INHIBITION DE LA VOIE DE COMPLEMENT ALTERNATIVE POUR LE TRAITEMENT DE LESIONS TRAUMATIQUES DU CERVEAU, DE LESIONS DE LA MOELLE EPINIERE ET DE CONDITIONS APPARENTEES
MUSC FOUNDATION FOR RESEARCH DEVELOPMENT;THE REGENTS OF THE UNIVERSITY OF COLORADO
发明人:
HOLERS, VERNON MICHAEL,THURMAN, JOSHUA M.,TOMLINSON, STEPHEN,STAHEL, PHILIP F.
申请号:
CA2610340
公开号:
CA2610340C
申请日:
2006.05.26
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Disclosed is the use of agents and compositions that selectively inhibit thealternative complement pathway for the inhibiting or treating physiologicaldamage resulting from traumatic brain injury (TBI), spinal cord injury (SCI),or related conditions. Preferred reagents for use in inhibition of damageresulting from TBI or SCI include those that inhibit factor B, with anti-factor B antibodies representing a particularly preferred agent.