LEE, IN HYUNKR,이인현,SON, MIN HEEKR,손민희,PARK, YEONG TAEKKR,박영택,JO, YEONG WOOKR,조영우,LEE, HAN KOOKR,이한구
申请号：
KR1020150108004
公开号：
KR1016122590000B1
申请日:
2015.07.30
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
Provided in the present invention are a pharmaceutical composition for oral administration, and a manufacturing method thereof. The composition essentially comprises: (a) 4 to 40 wt% of a taxane (b) 10 to 40 wt% of polyoxyl glyceryl fatty acid ester (c) 30 to 70 wt% of mono-oleyl glycerol and (d) 5 to 30 wt% of a surfactant. According to the present invention, the method is capable of manufacturing a clear solution containing taxanes in high concentrations.COPYRIGHT KIPO 2016본 발명은 (a) 탁산 4 내지 40 중량%, (b) 폴리옥실 글리세릴 지방산 에스테르 10 내지 40 중량%, (c) 모노올레일 글리세롤 30 내지 70 중량%, 및 (d) 계면활성제 5 내지 30 중량%로 필수적으로 구성된 경구 투여용 약학 조성물 및 이의 제조방법을 제공한다.
