A stent delivery system includes a handle and an elongate catheter extending from the handle, and defining a leading end and a trailing end, and having a longitudinal axis. The elongate catheter includes an inner member, an outer member mounted about the inner member and adapted for longitudinal movement relative to the inner member from an extended position to a retracted position and a stent mounted about the inner member. The stent delivery system also includes a thumbwheel mounted to the handle and operatively connected to the outer member, and a lock member releasably mountable to the handle. The thumbwheel is adapted for rotational movement to cause corresponding movement of the outer member from the extended position to the retracted position. The lock member is adapted to engage at least one of the outer member and the thumbwheel to prevent movement thereof when the lock member is secured relative to the handle, and is adapted to release the at least one of the outer member and the thumbwheel when the lock member is released relative to the handle. The lock member may be adapted to engage each of the outer member and the thumbwheel to prevent respective movement thereof when the lock member is secured relative to the handle and adapted to release each of the outer member and the thumbwheel when the lock member is released relative to the handle.