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Device for in vivo delivery of bioactive agents and method of manufacture thereof
专利权人:
Christopher T. Boyle
发明人:
Christopher T. Boyle,Steven R. Bailey,Denes Marton,Christopher E. Banas
申请号:
US10936884
公开号:
US09107605B2
申请日:
2004.09.09
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention consists of an implantable structural element for in vivo controlled delivery of bioactive active agents to a situs in a body. The implantable structural element may be configured as an implantable prosthesis, such as an endoluminal stent, cardiac valve, osteal implant or the like, which serves a dual function of being prosthetic and a carrier for a bioactive agent. Control over elution of the bioactive agents occurs through a plurality of cantilever-like cover members which prevent drug elution until an endogenous or exogenous stimulus causes the cover members to open and permit drug elution.
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