The invention concerns a tube pump comprising a cradle (1) with a cavity (11) suitable for the accommodation of a tube clamp (2). It further concerns a tube clamp (2) for a flexible tube, the tube clamp being suitable for accommodation in a tube pump, the tube clamp having a mobile part and an immobile part (20) designed to penetrate at least partly into a housing (11) realized in the tube pump. The invention also concerns a perfusion set. Finally, the invention concerns a system comprising a tube pump and a tube clamp. In order to provide a system comprising a tube pump and a tube clamp with improved operation safety, the tube pump has a cavity (11) with at least one protrusion (14) and the tube clamp (2) has means (21) for snapping attachment of the tube clamp behind the protrusion (14). This arrangement allows to fix the tube clamp (2) safely in the cavity (11) and to give furthermore a feedback to the user because he feels (and he might in addition hear) that the tube clamp has snapped behind the protrusion. A further advantage resides in the fact that the solution according to the present invention can be put in place without significantly increasing the costs of the parts involved in the invention.
