ELLA, Krishna Murthy,PRASAD, Sai Devarajulu,VADREVU, Krishna Mohan
申请号：
TN2018000436
公开号：
TN2018000436A1
申请日:
2017.06.13
申请国别(地区):
TN
年份:
2020
代理人:
摘要：
A buffer free, acid stable, low dose volume rotavirus vaccine is disclosed. The vaccine is available in dose volume of less than 1 ml per dose for oral administration and it is without any buffer. The vaccine also does not require pre or post administration of any antacid at the time of oral administration of the vaccine to the subject to neutralize the stomach acid. The vaccine exemplifies nominal drop in vaccine titer at pH 2-4 for a time span of 30 minutes. The vaccine is stable at -20°C for at least 60 months.
