The invention relates to a medicinal composition containing levocarnitine and hydroxybenzene sulfonate. The invention also relates to a method for adjusting serum creatinine (Scr) and/or urea nitrogen (BUN) level. The invention further relates to a method for treating and/or preventing related diseases influencing renal function, such as various primary glomerulonephritis, secondary glomerulonephritis, diabetic nephropathy, renal insufficiency, nephrotic syndrome and even renal failure and uremia, and complication caused by the related diseases and/or symptoms influencing renal function, such as diseases and/or symptoms of cardiovascular diseases, diabetes and the like.
