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HSP70 MODULATORS AND METHODS FOR MAKING AND USING THE SAME
专利权人:
Memorial Sloan Kettering Cancer Center
发明人:
Gabriela Chiosis,Yanlong Kang,Hardik J. Patel,Maulik Patel,Stefan Ochiana,Anna Rodina,Tony Taldone,Liza Shrestha
申请号:
US16179155
公开号:
US20190241526A1
申请日:
2018.11.02
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention, among other things, provides compounds and compositions thereof for use in the modulation of Hsp70. In some embodiments, the present invention provides a method for inhibiting Hsp70 activity. In some embodiments, the present invention provides a method of treating a subject suffering from or susceptible to a disease, disorder, or condition responsive to Hsp70 inhibition comprising administering to the subject a therapeutically effective amount of a provided compound. In some embodiments, the present invention provides a method for treating or preventing cancer in a subject suffering therefrom, comprising administering to a patient in need thereof a therapeutically effective amount of a provided compound.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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