Gabriela Chiosis,Yanlong Kang,Hardik J. Patel,Maulik Patel,Stefan Ochiana,Anna Rodina,Tony Taldone,Liza Shrestha
申请号:
US16179155
公开号:
US20190241526A1
申请日:
2018.11.02
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention, among other things, provides compounds and compositions thereof for use in the modulation of Hsp70. In some embodiments, the present invention provides a method for inhibiting Hsp70 activity. In some embodiments, the present invention provides a method of treating a subject suffering from or susceptible to a disease, disorder, or condition responsive to Hsp70 inhibition comprising administering to the subject a therapeutically effective amount of a provided compound. In some embodiments, the present invention provides a method for treating or preventing cancer in a subject suffering therefrom, comprising administering to a patient in need thereof a therapeutically effective amount of a provided compound.