A cartridge of an intraocular lens inserter comprises an insertion nozzle, having a distal insertion channel; an infra-ocular lens (IOL)-folding stage, to receive and to fold an IOL, prox imal to the insertion nozzle, and having a proximal insertion channel; and an SOL-guIding structure. The iOL-guiding staicture can inckde a first proximal guiding groove, or a first proximal guiding rib, or both, formed in the lOL-foiding stage. An intraocular leas inserter comprises an inserter cylinder; a push-rod, partially in the inserter cylinder: a cartridge- receiving insertion end, to receive a cartridge that includes an insertion nozzle, having a distal insertion channel; an iOL-faidiog stage, proximal to the insertion nozzle, having a proximal insertion channel; and an lOL-guiding structure.