Methods are described for improving sexual health by administering a composition in an effective amount to a subject in need thereof. More particularly, methods are described for improving sexual health by administering a macroalgae composition including a macroalgae extract, comprised of saturated and unsaturated fatty acids in a ratio of at or about 1:0.5 to at or about 1:10. The composition is prepared by solvent extraction of macroalgae selected from green, red and/or brown seaweeds or the combinations thereof. Effects are evaluated on biomarkers related to sexual health such as testosterone synthesis, nitric oxide synthesis, phosphodiesterase 5 and 11.