MONOCLONAL ANTIBODIES

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专利权人:

ZE REJENTS OV ZE UNIVERSITI OV KALIFORNIA

发明人:

AKASOGLU, KATERINA

申请号：

GEAP2010012676

公开号：

GEP20146214B

申请日:

2010.09.30

申请国别(地区):

GE

年份:

2015

代理人:

摘要：

The present invention provides an isolated antibody that binds a fibrin or fibrinogen &lambda；C domain. In various aspects, the antibody inhibits microglial adhesion to the fibrin or fibrinogen &lambda；C domain, inhibits Mac-1 binding to the fibrin or fibrinogen &lambda；C domain, and/or suppresses clinical symptoms, wherein pathology is selected from following group: disseminated sclerosis, rheumatoid arthritis and cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/