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Predictive biomarkers of clinical response to anti-LPS immunoglobulin treatment
专利权人:
IgNova GmbH;Julius-Maximilians-Universitat Wurzburg
发明人:
Sprotte, Gunter,Waaga-Gasser, Ana Maria
申请号:
AU2016249856
公开号:
AU2016249856A1
申请日:
2016.04.14
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention relates to the biomarkers for predicting the clinical response to anti-LPS immunoglobulin treatments in patients in need thereof. In particular, the invention provides methods for predicting the clinical response to an anti-LPS immunoglobulin treatment in a patient in need thereof, said method comprising the steps of evaluating the expression of a predictive biomarker selected from the group consisting of CD14, CD68, TLR4, TLR7, IL6, IL8, IL10, IFN-alpha, IGF1, CXCL1, CXCL9, CXCL10, RAGE, GDNF, BCHE, and combination thereof, in said patient.
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