The present invention relates to an aqueous solution comprising between 0,1% and 3% hyaluronic acid and its use in medicine. It also relates to a cather with cannulas for vascular puncture with double or triple cut tip comprising, (i) an outer part (non-cutting element), a tube-like construction of 0,9 to 1,2 mm in outer diameter, and 0,8 - 1,1 mm inner diameter which is slightly flexible, of a metal or plastic material, (a) the tip zone being optionally tapered to ease introduction, (b) the edges being optionally rounded to provide atraumatic advancement (c) optionally with a Luer-lock connector. (ii) a hollow needle which is flexible and bendable (c) optionally with a transparent flashback chamber, wherein (d) the diameter of the needle is below the diameter of the catheter, wherein (iii) the needle and catheter are connected by a temporary lock to ensure the needle tip is fixed in adequate position outside the catheter during skin puncture and introduction towards the target region.
