The present invention relates to the compounds and composition that are used to expand the CD34+ cell numbers transplanted with what. The invention further relates to the cell mass of the candidate stem cell (HSC) comprising having expanded and its patient with inherited immunological defects and autoimmune disease and various disorder of hematopoietic system is being treated with what with rebuild hematopoietic cell system and immune system defence self or allograft in purposes.本發明涉及用來擴增用於移植的CD34+細胞數目的化合物和組合物。本發明進一步涉及包含擴增了的造血幹細胞(HSC)的細胞群以及其在用於對具有遺傳免疫缺陷和自身免疫疾病以及各種造血系統病症的患者進行治療以重建造血細胞系和免疫系統防禦的自體或同種異體移植中的用途。