CHIMERIC ANTIGEN RECEPTORS (CAR) TO SELECTIVELY TARGET PROTEIN COMPLEXES

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专利权人:

THE UNIVERSITY OF TEXAS SYSTEM;BOARD OF REGENTS

发明人:

Laurence J.N. COOPER,Bipulendu JENA

申请号：

US15524321

公开号：

US20170334968A1

申请日:

2015.11.04

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Chimeric antigen receptor (CAR) constructs are provided that are able to selectively bind to specific protein complexes, such as HER 1/HER3 heterodimer receptors. CAR T-cells comprising these constructs can be used to safely and efficiently target cancer cells expressing specific protein complexes.

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中国工程科技知识中心

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