The present invention relates to use of a composition for the manufacture of a medicament and a method for inhibiting the formation of body fat. The composition includes lactoferrin and a trivalent chromium compound. Herein, the chromium compound is selected from the group consisting of chromium (III) chloride hexahydrate, chromium (III) chloride, chromium (III) acetate, chromium (III) sulfate, chromium picolinate, chromium nicotinate, chromium GTF, chromium yeast extract, other inorganic salts of trivalent chromium, other organic salts of trivalent chromium, and combinations thereof. Accordingly, the composition of the present invention can assist in transmitting glucose from cells to muscle tissues and thereby reducing the storage of fat converted from glucose to achieve the purpose of controlling body weight.本發明係有關於一種減少體脂肪形成之組成物及其方法,該組成物包括:一乳鐵蛋白;以及一三價鉻化合物,其中,該三價鉻化合物係選自由六水三氯化鉻、三氯化鉻、醋酸鉻、硫酸鉻、吡啶甲酸鉻、菸鹼酸鉻、耐糖因子鉻、酵母鉻、其他之無機三價鉻、其他之有機三價鉻以及其組合物所組成之群組。據此,本發明之組成物可藉由協助細胞中之葡萄糖運送至肌肉組織中利用,且減少葡萄糖轉化成脂肪儲存,而達到體重控制的目的。