您的位置: 首页 > 农业专利 > 详情页

PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF HYPERACTIVITY OF THE BLADDER
专利权人:
ИНК. (US);ТЕРАВИДА
发明人:
ПАБОРДЖИ Мехди (US),ТУОХИ III Роберт В. (US),ФРИД Питер Р.П. (US),ФЛЮГЕЛЬ Роджер С. (US)
申请号:
RU2012143705/15
公开号:
RU2012143705A
申请日:
2011.04.01
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A pharmaceutical composition comprising a plurality of first granules, each of which contains: a core; a first layer comprising pilocarpine or cevimelin or a pharmaceutically acceptable salt thereof; and a second layer containing the first polymer. 2. The pharmaceutical composition according to claim 1, characterized in that the core contains a cellulosic polymer or silicon dioxide or sugar selected from the group consisting of glucose, sucrose, lactose, mannitol, xylitol and sorbitol. The pharmaceutical composition according to claim 1, characterized in that the core comprises from about 10% to about 50% of the total weight of the finished granule. The pharmaceutical composition according to claim 1, characterized in that the first layer comprises from about 1% to about 50% of the total weight of the granules. The pharmaceutical composition according to claim 1, characterized in that the first polymer contains a soluble film-forming polymer selected from the group consisting of hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, carboxymethyl cellulose, maltodextrin, sucrose, modified starch, alginic acid salt, carrageenan polyvinyl chloride or polyvinyl polypyrrolidone (PVPP) .6. The pharmaceutical composition according to claim 1, characterized in that the second layer further comprises an insoluble film-forming polymer selected from the group consisting of ethyl cellulose, cellulose acetate phthalate, hydroxypropyl methyl cellulose phthalate, insoluble gums, polymethacrylate, polyvinyl alcohol, shellac and polyvinyl acetate. The pharmaceutical composition according to claim 1, characterized in that the granule further comprises a tackifier or a substance to promote1. Фармацевтическая композиция, содержащая множество первых гранул, каждая из которых содержит:ядро;первый слой, содержащий пилокарпин или цевимелин или их фармацевтически приемлемую соль; ивторой слой, содержащий первый полимер.2. Фармацевтическая композиция по п.1, отл
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充